NVIDIA Launches Nemotron 3.5 Open Model Family, Cosmos World Models, and 13x Faster BioNeMo RFD4-Proteina
During the GTC Berlin keynote, NVIDIA unleashed a sweeping array of open-weights domain-specific foundation models. The release highlights include the multimodal Nemotron 3.5 Super VL, the lightweight Nemotron 3.5 Bolt series, and the end-to-end Nemotron Retriever suite for embedding, reranking, and document OCR. For physical AI, NVIDIA debuted the Cosmos world models and Alpamayo 2 Edge autonomous driving models. In life sciences, NVIDIA and the Baker Lab released BioNeMo RFD4-Proteina, which establishes state-of-the-art accuracy across more than 10 protein design benchmarks while synthesizing 200-amino-acid binders roughly 13x faster than RFdiffusion3.
Key Takeaways
- NVIDIA released an extensive open-weights portfolio at GTC Berlin: Nemotron 3.5 Super VL, Bolt 4GB edge variants, and Cosmos world models
- Unveils the full Nemotron Retriever suite for embedding, reranking, and multimodal document parsing, boosting enterprise RAG fidelity
- Co-developed BioNeMo RFD4-Proteina with the Baker Lab, leading on over 10 structural protein design benchmarks
- Synthesizes 200-amino-acid de novo proteins 13x faster than RFdiffusion3, dramatically shortening computational drug discovery timelines
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