SGLang v0.5.22 Released: DeepSeek-V4.1 Throughput Jumps 2.3x on H200 and 1.9x on MI355X, InstantTensor Loads Models 10x Faster
The SGLang team released v0.5.22 featuring 950 PRs from 245 contributors: DeepSeek-V4.1 delivers up to 2.3x more throughput per GPU on NVIDIA H200 and 1.9x on AMD MI350X/MI355X via DSpark. The new InstantTensor loader cuts model loading time by 10x. B200 decodes Qwen3.8-Flash-Next 12% faster, while B300 speeds up GLM-5.3-Flash by 10% and yields 1.85x decode throughput for MiMo-V2.6-Pro. SGLang also adds native Apple Silicon PyTorch support and ComfyUI integration.

Key Takeaways
- SGLang v0.5.22 released with 950 PRs from 245 contributors across heterogeneous platforms
- DeepSeek-V4.1 achieves up to 2.3x throughput per GPU on NVIDIA H200 and 1.9x on AMD MI350X/MI355X via DSpark
- New InstantTensor loader speeds up large model checkpoint ingestion by 10x
- Qwen3.8-Flash-Next decodes 12% faster on B200; MiMo-V2.6-Pro reaches 1.85x decode throughput on B300
- PD disaggregation cuts p95 TTFT in half (-50%) on long prompts, alongside native Apple Silicon and ComfyUI diffusion support

