Seattle startup Nuance Labs released Nuplex 1.0 (Nuance Full-duplex) on November 9, a full-duplex audiovisual foundation model that listens and speaks at the same time, along with Emma, the first AI persona built on it. Emma nods, smiles and uses gaze to signal turn-taking while the user is still speaking instead of waiting for them to finish. On 1,785 questions drawn from recordings of real conversations, the company says Nuplex reply timing overlaps the original human speaker 89% of the time, versus 35% for the next closest system. Emma can be tried in a browser with no sign-up, and the Nuplex Beta API is open, though deliberately restricted: no cloning of real people, watermarked video, English only, adults only, and no healthcare or under-18 use for now.
Key Takeaways
- ✓Company figures: on 1,785 real-conversation questions, Nuplex reply timing overlaps the human speaker 89% of the time vs 35% for the next closest system; compared systems include PersonaPlex, Moshi, GPT-Live and Gemini Live
- ✓18 months of research; Emma's face and voice are licensed from a real actress who helped capture how she actually listens, reacts and speaks, rather than an averaged face
- ✓The Nuplex Beta API lets developers brief a persona with their own prompt and hand longer tasks to their tools in the background mid-call; during the beta the language model is served by Nuance
- ✓Limits: no uploading faces or voices and no cloning real people, API video carries a visible watermark; English only, 18+ only, and no healthcare or under-18 use yet
- ✓Availability: the US (except Colorado, Connecticut, Illinois and Texas), the EU, the UK, and Canada (except Quebec)

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Background and Pain Points
Most voice assistants and digital humans are half-duplex: they wait for the user to finish, then answer, and while you talk the on-screen face either stares blankly or loops a canned animation. Real people nod, frown and use their eyes to signal it is your turn. Nuance Labs, co-founded by former Apple researcher Fangchang Ma (MIT PhD), argues that what digital humans lack is not a more realistic face but the right timing.
Architecture Highlights
Nuplex is a full-duplex audiovisual foundation model: it takes in the user's voice and camera feed while generating its own voice and facial video, without waiting for the user to stop. Gaze is treated as a turn-taking signal, so Emma visibly reacts while listening. Her face and voice are licensed from a real actress who helped record how she actually listens and reacts, and her personality is designed to hold opinions and disagree rather than flatter. Reasoning still comes from a language model; Nuplex can work with any LLM, but Nuance serves one itself during the beta. Parameter counts and training data size were not disclosed.
Benchmarks
These are company figures. Nuance took 1,785 questions from its own recordings of real conversations and compared when each system started replying with when the original human answered. Nuplex overlapped 89% of the time; the next closest system reached 35%. Nuance says open models such as PersonaPlex and Moshi are tuned to answer fast, while GPT-Live and Gemini Live answer later, and those two were measured through public APIs that include network time. The company also admits there is no benchmark yet that captures the real experience of audiovisual full-duplex chat. No independent evaluation has been published.
Getting Started
Visit emma.nuancelabs.ai to video chat with no account; headphones help because background noise hurts turn-taking. Developers can request the Nuplex Beta API on Nuance's platform, brief a persona with a prompt, and let it hand longer tasks to their own tools mid-conversation. Known gaps: English only, occasional interruptions or long pauses, lip sync and gaze glitches on poor connections, and early-stage visual understanding. It suits interview practice, customer support and coaching; healthcare and education are not available yet.
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